Downtown Dubuque is the location of the city's central business district and many of its government and cultural institutions. It is the center of Dubuque's transportation and commercial sectors, and functions as the hub to the various outlying districts and neighborhoods. It is located in the east-central portion of the city, along the Mississippi River, and includes all of the area north of Maus Park, south of 17th Street, east of the bluffline, and west of the river.
The area is made up of several distinct neighborhoods, each of which has a unique history and character. These neighborhoods include: Cable Car Square/Cathedral Square, the Central Business District, Jackson Park/Upper Main, Lower Main, and the Warehouse District. An area of special note within Downtown Dubuque is the Port of Dubuque, which has seen a massive amount of new investment and new construction. The downtown area includes a number of significant buildings, many of which are historic, reflecting the city's early and continuing importance to the region. Important sites downtown include:
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